WebExplore 15 research articles published by the author Tohru Fukuyama from Nagoya University in the year 2016. The author has contributed to research in topic(s): Total synthesis & Alkylation. The author has an hindex of 62, co-authored 372 publication(s) receiving 12191 citation(s). Previous affiliations of Tohru Fukuyama include University of … WebHuperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other food Huperzia species, including H. elmeri, H. carinat, and H. aqualupian. Huperzine A has been investigated as a treatment for neurological conditions such as Alzheimer's disease, but a meta-analysis of those studies …
Secondary metabolites of endophytic fungi isolated from Huperzia …
WebOct 30, 2014 · An enamine bromofunctionalization strategy has been utilized in the total syntheses of (−)-huperzine Q and (+)-lycopladines B and C. Other notable features of the syntheses include an ethylene-accelerated carbonyl–olefin metathesis, an unprecedented X-ray crystal structure of an unusual epoxyamine intermediate, and its first synthetic … WebAug 17, 2012 · The total synthesis of Lycopodium alkaloid (−)-huperzine A has been accomplished in 10 steps with 17% overall yield from commercially abundant (R) … taos zappos
Enantioselective Pd-catalyzed tandem allylic alkylation reaction …
WebJan 1, 1989 · The natural product Huperzine A isolated from Huperzia serrata is a targeted inhibitor of acetylcholinesterase that has been approved for clinical use in the treatment … WebDec 3, 2013 · Huperzine A, huperzine B, and huperzine U are congeners isolated from the Chinese herb Huperzia serrata (=Lycopodium serratum) in minuscule amounts. The most … WebTotal synthesis offers an alternative potential source of huperzine. An enantioselective synthesis is highly desirable, because (+)-huperzine A is significantly less potent than the natural (−)-antipode (1). 7 The first total syntheses of (±)-huperzine A were reported by Kozikowski and Xia 8 and Qian and Ji. 9 A chiral auxiliary-based route ... tao tai khoan google drive