WebT1 - Three-arm phase III trial comparing cisplatin plus 5-FU (CF) versus docetaxel, cisplatin plus 5-FU (DCF) versus radiotherapy with CF (CF-RT) as preoperative therapy for locally advanced esophageal cancer (JCOG1109, NExT Study) AU - Nakamura, Kenichi. AU - Kato, Ken. AU - Igaki, Hiroyasu. AU - Ito, Yoshinori. AU - Mizusawa, Junki Web1 feb 2024 · In a recent phase 3 clinical trial, JCOG1109 NExT trial, conducted in Japan, DCF regimen has been shown to be optimal as neoadjuvant therapy for stage IB-III …
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238 Background: Neoadjuvant treatment is the standard care for locally advanced esophageal squamous cell cancer (ESCC). JCOG1109 (UMIN000009482) compared the doublet and triplet of chemotherapy and chemoradiotherapy as neoadjuvant treatment. Methods: Eligible patients (pts) with ESCC of clinical stage IB, II, III (excluding T4) (UICC 7th) from 44 institutions were randomized 1:1:1 to ... Web8 feb 2024 · Docetaxel plus neoadjuvant cisplatin and 5-fluorouracil (DCF) chemotherapy was superior to CF chemotherapy alone in patients with locally advanced oesophageal cancer, the primary analysis of the phase 3 JCOG1109 NExT trial showed. Moreover, the toxicity profile of the DCF combination regimen was manageable. blue mic boom arm
Next study (JCOG1109): A three-arm randomized phase III study …
WebA randomized controlled phase III trial comparing two chemotherapy regimen and chemoradiotherapy regimen as neoadjuvant treatment for locally advanced esophageal … WebReflections and next step directions from your new President; Striving for greater equality; Care at the core of the ESMO Vision 2025; ... named JCOG1109. He also committed to the international phase III trial of oesophageal and gastric cancer with … Webjcog1109 (next):dcf 成为食管癌术前治疗的标准方案 这是值得关注的第一个来自日本的研究成果,jcog1109(next)临床研究。 本研究的对象为可切除的局部晚期食管癌,这个分期 … blue mice software