WebJun 25, 2024 · Erythropoietin production is decreased by both acute and chronic causes of kidney disease, and chronic kidney disease is known to be a common cause of non-regenerative anemia in the cat. 27–29 Production of neutralizing antibodies against erythropoietin has occasionally been associated with the administration of ESAs, and … WebSep 30, 2024 · This interim study data strongly validates that SB-001’s expressed feline erythropoietin (fEPO) results in a prolonged therapeutic effect after a single treatment …
Expression of erythropoietin in cats treated with a ... - PubMed
WebNov 25, 2024 · Kindred Biosciences (NASDAQ:KIN)-3.2% after-hours as it discloses the suspension of its feline recombinant erythropoietin program following an "adverse event."; Citing the impact of safety profile ... WebIn this in vitro study, feline erythropoietin cDNA was cloned from feline renal tissue and utilized in the construction of a replication-defective lentiviral vector. The native recombinant feline erythropoietin (rfEPO) sequence was confirmed by sequencing. Upon viral vector infection of human 293H cells, Crandall Renal Feline Kidney cell line ... stephen dodd comedian
Feline Erythropoietin (EPO) Do-It-Yourself ELISA, ≤20 Plates
WebMay 6, 2024 · Developing ways to deliver feline erythropoietin genes to cats that are deficient in this hormone enables us to avoid frequent injections of foreign protein . In vitro studies on the delivery of the erythropoietin gene to cells have demonstrated the feasibility of using a replication-defective delivery system for the production of biologically ... WebThe Feline Erythropoietin Do-It-Yourself ELISA contains capture antibody, protein standard, and detection antibody for development of a Feline EPO ELISA. The antibodies have been determined to function in an ELISA with the standard provided. Optimal buffers, concentrations, incubation times, incubation temperatures, and methods for the ELISA ... WebObjective: To use transient and stable transfection of Chinese hamster ovary cells to clone the gene encoding feline erythropoietin (feEPO) protein, characterize the expressed protein, and assess its biological activity. Sample population: Cultures of Chinese hamster ovary or TF-1 cells. Procedure: The gene encoding feEPO was cloned into a eukaryotic … stephen doctor