Cisplatin salt wasting
WebAug 1, 2024 · Cisplatin (CDDP) is an important anticancer drug. A common side effect of CDDP is renal salt and water-wasting syndrome (RSWS). The origin of RSWS is … WebCisplatin-Induced Renal Salt Wasting Requiring over 12 Liters of 3% Saline Replacement Case Rep Nephrol. 2024;2024:8137078. doi: 10.1155/2024/8137078. Epub 2024 May 10. Authors Phuong-Chi Pham 1 , Pavani Reddy 1 , Shaker Qaqish 1 , Ashvin Kamath 1 , Johana Rodriguez 2 , David Bolos 2 , Martina Zalom 2 , Phuong-Thu Pham 3 …
Cisplatin salt wasting
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WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. During his five-day hospital course, his renal parameters steadily improved, and his serum sodium improved from 124 mEq ... WebRenal salt wasting: urine Na will be high. Causes include salt-wasting nephropathy, adrenal insufficiency, cisplatin, and thiazide diuretic use. Euvolemic: Hypothyroidism: check TSH. Glucocorticoid deficiency: check AM cortisol.
WebWe diagnosed this clinical condition as renal salt-wasting syndrome (RSWS) on the basis of dehydration and high urinary sodium excretion at the onset. In the second course of chemotherapy, CDDP was replaced with carboplatin (CBDCA); consequently, hyponatremia was not observed.
WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting … WebNational Center for Biotechnology Information
WebCisplatin Induced Renal Salt Wasting Syndrome: An Uncommon Diagnostic Distinction Session Information. Fluid, Electrolyte, and Acid-Base Disorders: Case Reports ... and recovery is the rule although recurrence is common. While carboplatin is less toxic, cisplatin has unequivocal superiority in most of the cancers in which it is used, making it ...
WebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical... birds of southern africaWebCisplatin-induced renal salt wasting requiring over 12 liters of 3% saline replacement. Case Rep Nephrol 2024; 2024:8137078 Cadacio C, Pham PT, Bhasin R, Kamarzarian A, Pham PC. Multiple electrolyte and metabolic emergencies in a single patient. Case Rep Nephrol 2024:4521319 birds of southern louisianaWebFeb 16, 2024 · Cisplatin Carboplatin 11% (carboplatin likely lower) SIADH, renal salt wasting (tubular damage) Cyclophosphamide Ifosfamide 9%–52% SIADH BCR-ABL tyrosine kinase inhibitors Imatinib 9%–13% SIADH BRAF and VEGF tyrosine kinase inhibitors Axitinib Sorafenib Brivanib Pazopanib Sunitinib 16%–39% SIADH EGFR … birds of southern caWebBoth renal salt-wasting syndrome (RSWS) and syndrome of inappropriate antidiuretic hormone secretion (SIADH) have been reported as the underlying mechanisms for … birds of southern massachusettsWebRenal salt wasting syndrome has been described in 17 case reports since 1984. It is a rare side effect of cisplatin that manifests with polyuria, hypovolemia, and hyponatremia, … birds of southern michiganWebCisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1 mg twice daily, oral salt tablets 1 g QID, sodium bicarbonate tablets … danbury medical group fax numberWebOct 6, 2016 · In the clinical setting, the most common and important manifestation of cisplatin nephrotoxicity is AKI, which can be progressive and even irreversible. Other renal manifestations include hypomagnesaemia, salt wasting, a … danbury medical group moving