2024 Cisplatin drugbank

Cisplatin drugbank

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August undefined, 2024

WebGeneric Name Digoxin DrugBank Accession Number DB00390 Background. Digoxin is one of the oldest cardiovascular medications used today. 5 It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. 7 Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. 25 This drug originates … WebIdentification Summary. Pentoxifylline is a methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.. Generic Name Pentoxifylline DrugBank Accession Number DB00806 Background. Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties …

Cisplatin Cl2H6N2Pt - PubChem

WebDrugBank Accession Number DB05773 Background. Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to … WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. Structured drug data for data science & ML. ... Cisplatin (DB00515) Docetaxel (DB01248) Erlotinib (DB00530) Filgrastim (DB00099) Pegfilgrastim (DB00019) uft repair

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WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: therapeutic potential for ovarian cancer. Cancer Sci. 2009 Dec;100(12):2459-64. doi: 10.1111/j.1349 … WebCisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare cases of clinically apparent, acute liver injury. uft retro pay

Erlotinib Completed Phase 2 Trials for Stage IV Non-small Cell …

WebDiscover expert tips and tricks on loading DrugBank SQL Files Read Guide. Durvalumab Recruiting Phase 2 Trials for Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC) / Adenocarcinoma of the Lung / Stage III Lung Cancer AJCC v8 / Lung Large Cell Carcinoma Treatment. Back to Durvalumab. Indications WebSep 18, 2024 · NCBI Bookshelf uft retro pay latest newsWeb846 rows · Generic Name. Sofosbuvir. DrugBank Accession Number. DB08934. … uft release

"WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... (CBDCA, JM8), an analogue of cisplatin showing reduced toxicity in preclinical studies, was evaluated in 60 patients. Doses were given initially every 3 weeks and escalated from 20 to 520 mg/m2. Following … " - Cisplatin drugbank

Cisplatin drugbank

Daunorubicin: Uses, Interactions, Mechanism of Action - DrugBank

WebGeneric Name Ondansetron DrugBank Accession Number DB00904 Background. A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Cisplatin DrugBank Accession Number DB00515 Background. Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and … See more

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WebBaricitinib. Baricitinib is a Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. WebThe present findings suggest that induction of P450 by cisplatin may take part in the renal injury or nephrotoxicity of cisplatin. DrugBank Data that Cites this Article Drug Enzymes. Drug Enzyme Kind Organism Pharmacological Action Actions; Cisplatin: Cytochrome P450 4A11: Protein: Humans:

WebDisease. Known drugs (DrugBank IDs). Top 10 ranked predictions.; HD (OMIM ID: 143100) Baclofen (DB00181) Olanzapine (DB00334), Quetiapine (DB01224), Ziprasidone ... WebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research. Drug Datasets. ... (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin. Biochem Pharmacol. 1998 Oct 15;56(8):1013-21.

WebPubMed Central (PMC) WebCisplatin Prices, Coupons and Patient Assistance Programs. Cisplatin is a member of the alkylating agents drug class and is commonly used for Anal Cancer, Bladder Cancer, …

WebMar 29, 2024 · Reviewed on 3/29/2024. Cisplatin: An anticancer drug that belongs to the family of drugs called platinum compounds. Cisplatin is used in the treatment of a wide …

WebNov 30, 2015 · Thiosulfuric acid is a sulfur donor used sequentially with sodium nitrite for the reversal of life-threatening acute cyanide poisoning. Also used to reduce the risk of ototoxicity associated with cisplatin. Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. thomas gahan bath house chicagoWebNavigate to DrugBank.com to check out our commercial products, use cases and more! DrugBank For Commercial Research ... Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest. Invest New Drugs. 2011 Aug;29(4):627 ... thomas gagonWebDurvalumab (בתעתיק עברי: דורוואלומאב; שם מסחרי: Imfinzi) היא תרופה המאושרת על ידי ה-FDA, לטיפול בסרטן שפותחה על ידי חברת Medimmune\Astrazenica.זהו נוגדן מונוקלונאלי אנושי (Immunoglobulin G1 Kappa(IgG1k)), אשר חוסם את האינטראקציה בין החלבון החוץ תאי PD-1 ... thomas gahan attorneyWebSep 15, 2024 · DESCRIPTION. Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL … uft researchWebGeneric Name Adalimumab DrugBank Accession Number DB00051 Background. Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. 2,3 It was originally launched by Abbvie in the U.S. and approved in 2002 by the … uft retro payment scheduleWebAbstract. Since response to platinum-based therapy in non-small-cell lung cancer (NSCLC) is poor, the present study was designed to rationally identify novel drug combinations in cell models including the A549 cell line and the cisplatin-resistant subline A549/Pt, characterized by reduced sensitivity to cisplatin-induced apoptosis and by upregulation … uft rigs of rodsWebMitoxantrone has been shown in vitro to inhibit B cell, T cell, and macrophage proliferation and impair antigen presentation, as well as the secretion of interferon gamma, TNFa, and IL-2. Mechanism of action. Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and ... thomas gahner jamestown nd